Artificial intelligence can increase the accuracy of gestational age estimation

06 January 2023

2 minutes of studying

Lee experiences that he owns a stake in Google as a part of his normal worker compensation plan and has filed a patent for Google (20220354466). For related monetary disclosures by all different authors, please check with the examine.

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Synthetic intelligence fashions educated to research ultrasounds may assist sonographers extra precisely predict gestational age, in keeping with revealed information. JAMA Community Open.

“Fetal ultrasonography is the cornerstone of prenatal imaging and supplies essential info to information maternal-fetal care, similar to estimated gestational age and evaluation of fetal development problems.” Chace Lee, MS, Wrote from Google Well being in Palo Alto, California, and colleagues. “At present, the scientific normal for estimating gestational age and diagnosing fetal development problems is ready by handbook acquisition of fetal biometric measurements similar to biparietal diameter, head circumference, stomach circumference, femur size, or crown-to-rump size.”

Data from Lee C et al.  JAMA Net On.  2023;doi:10.1001/jamanetworkopen.2022.48685.

Knowledge from Lee C et al. JAMA Internet On. 2023;doi:10.1001/jamanetworkopen.2022.48685.

As a result of estimation of gestational age is dependent upon the abilities and expertise of sonographers, the researchers have labored to develop synthetic intelligence programs to help sonographers of their predictions based mostly on work historical past.


For this examine, Lee and colleagues developed three AI fashions to find out gestational age. The primary mannequin estimated gestational age in days based mostly on fetal ultrasonography pictures captured throughout biometric measurements, the second analyzed 5 to 10-second flight movies captured simply earlier than picture seize, and the third mannequin, known as the ensemble mannequin, analyzed each pictures and flight. – to the movies. All fashions used Hadlock regression system for predictions.

Fashions had been educated and evaluated on potential information from the Fetal Age Machine Studying Initiative (FAMLI) examine, which enrolled pregnant ladies receiving antenatal care in Chapel Hill, North Carolina or Lusaka, Zambia. FAMLI sonographers manually assessed gestational age utilizing ultrasonography units with the built-in AI turned off. Researchers randomly assigned individuals to the coaching dataset (60%), the tuning dataset (20%), and the check dataset (20%).


The check dataset consists of 404 individuals (imply age, 28.8 years) who collectively participated in 677 examine visits.

The image-based mannequin extra precisely predicted gestational age as in comparison with the video-based mannequin (imply distinction in imply distinction (MAE), –1.13 days; 95% CI, –1.5 to –0.7) MAE’ at -1.48 days; 95% CI, -1.9 to -1.1) and ensemble mannequin (imply distinction in MAE, -1.51 days; 95% CI, -1.9 to -1.1).

Subgroup analyzes confirmed that AI fashions generalized nicely throughout second and third trimesters, units, and nations.

“We discovered that throughout the third trimester, our mannequin’s accuracy benefit over scientific normal fetal biometry elevated,” Lee and colleagues wrote. “That is particularly necessary as a result of it is true gestational age Forecasting within the third trimester is important for managing problems and making acceptable scientific selections concerning timing of supply.”

As well as, the ensemble mannequin included the Nationwide Institute of Youngster Well being and Human Growth (imply distinction, -1.23 days; 95% CI, -1.6 to -0.8) and Intergrowth-Twenty first (imply distinction, -2.69 days; 95% CI, –3.3 to –2.1) regression formulation.

“Sonographers are in excessive demand and infrequently have office or overuse accidents as a result of present screening necessities,” Lee and colleagues wrote. “Further research are wanted to discover whether or not an AI assistant can scale back scanning time, help sonographers, and decrease office accidents.”

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